NeuroNet: "Systematic Gene Identification and Functional Analyses in Common CNS Disorders"
Project List:
Animal Models for Parkinson Disease
Identification of disease genes in Alzheimer disease
Identification of inhibitors and modulators of beta- and gamma-secretase
Identification of genes that regulate A-beta42 levels
Transgenic mouse models to study family forms of cerebral amyloid angiopathy
The role of APP-dependent gene expression in Alzheimer Disease
Identification of genes involved in neuroprotection of Alzheimer disease
Identification of Genetic Risk Factors of Parkinsons Disease
Deciphering molecular pathways of monogenic forms of Parkinson disease by cell culture and animal models
Identification and validation of Parkinson disease relevant genes by functional genomics in cell culture and animal models
Molecular mechanisms of differntial vulnerability of dopaminergic neurons in Parkinson Disease
Functional Analyses in genetic mouse model of Parkinson Disease
Population Based Assessment of Genetic Risk Factors for Parkinson Disease (PD)
Identification of disease genes in bipolar affective disorder
Phenotype refinement in bipolar affective disorder as a prerequisite for the identification of disease genes
Identification of novel candidate genes in unipolar depression
Recruitment of a population based cohort of patients with bipolar affective disorder
Animal models for the analysis of candidate genes in affective disorder
Identification of quantitative trait loci involved in alcohol drinking, stress-induced alcohol drinking and relapse
A phenotype-driven ENU mutagenesis screen for the identification of genes involved in alcohol drinking and relapse
Conditional genetic manipulation of candidate genes involved in alcohol drinking, stress- induced alcohol drinking and relapse: role of L-type voltage-gated calcium Channels
The role of CRH/CRH-R1 pathway in alcohol drinking
The role of GR pathway in alcohol drinking, stress-induced alcohol drinking and relapse
Validation in humans of genes involved in alcohol drinking, stress-induced alcohol drinking and relapse
Gene identification in idiopathic seizure disorders
Molecular genetic dissection of idiopathic generalized epilepsy
Functional Anaylsis of ion channel mutations causing idiopathic generalized epilepsies
Identification and functional analysis of genes in human idiopathic epilepsy
CNS hyperexcitability in mouse models affecting ion transport diseases
Pathophysiological mechanisms of neurodegeneration and epilepsy in a mouse model of KCNQ/M-channel deficiency
Identification of disease genes in Alzheimer disease
Identification of inhibitors and modulators of beta- and gamma-secretase
Identification of genes that regulate A-beta42 levels
Transgenic mouse models to study family forms of cerebral amyloid angiopathy
The role of APP-dependent gene expression in Alzheimer Disease
Identification of genes involved in neuroprotection of Alzheimer disease
Identification of Genetic Risk Factors of Parkinsons Disease
Deciphering molecular pathways of monogenic forms of Parkinson disease by cell culture and animal models
Identification and validation of Parkinson disease relevant genes by functional genomics in cell culture and animal models
Molecular mechanisms of differntial vulnerability of dopaminergic neurons in Parkinson Disease
Functional Analyses in genetic mouse model of Parkinson Disease
Population Based Assessment of Genetic Risk Factors for Parkinson Disease (PD)
Identification of disease genes in bipolar affective disorder
Phenotype refinement in bipolar affective disorder as a prerequisite for the identification of disease genes
Identification of novel candidate genes in unipolar depression
Recruitment of a population based cohort of patients with bipolar affective disorder
Animal models for the analysis of candidate genes in affective disorder
Identification of quantitative trait loci involved in alcohol drinking, stress-induced alcohol drinking and relapse
A phenotype-driven ENU mutagenesis screen for the identification of genes involved in alcohol drinking and relapse
Conditional genetic manipulation of candidate genes involved in alcohol drinking, stress- induced alcohol drinking and relapse: role of L-type voltage-gated calcium Channels
The role of CRH/CRH-R1 pathway in alcohol drinking
The role of GR pathway in alcohol drinking, stress-induced alcohol drinking and relapse
Validation in humans of genes involved in alcohol drinking, stress-induced alcohol drinking and relapse
Gene identification in idiopathic seizure disorders
Molecular genetic dissection of idiopathic generalized epilepsy
Functional Anaylsis of ion channel mutations causing idiopathic generalized epilepsies
Identification and functional analysis of genes in human idiopathic epilepsy
CNS hyperexcitability in mouse models affecting ion transport diseases
Pathophysiological mechanisms of neurodegeneration and epilepsy in a mouse model of KCNQ/M-channel deficiency